| Rank | Movie Title (click to view) | Studio | Total Gross / Theaters | Opening / Theaters | Open | Close | ||
| 1 | 300 | WB | $193,402,459 | 3,280 | $70,885,301 | 3,103 | 3-Sep | - |
| 2 | Wild Hogs | BV | $145,260,566 | 3,401 | $39,699,023 | 3,287 | 3-Feb | - |
| 3 | Ghost Rider | Sony | $114,824,199 | 3,620 | $45,388,836 | 3,619 | Feb-16 | - |
| 4 | Norbit | P/DW | $94,772,025 | 3,145 | $34,195,434 | 3,136 | 2-Sep | - |
| 5 | Bridge to Terabithia | BV | $80,732,533 | 3,210 | $22,564,612 | 3,139 | Feb-16 | - |
| 6 | Blades of Glory | P/DW | $67,905,237 | 3,410 | $33,014,202 | 3,372 | Mar-30 | - |
| 7 | Stomp the Yard | SGem | $61,356,221 | 2,169 | $21,833,312 | 2,051 | 1-Dec | - |
| 8 | Meet the Robinsons | BV | $51,947,271 | 3,435 | $25,123,781 | 3,413 | Mar-30 | - |
| 9 | Music and Lyrics | WB | $49,933,530 | 2,955 | $13,623,630 | 2,955 | Feb-14 | - |
| 10 | TMNT | WB | $46,607,331 | 3,120 | $24,255,205 | 3,110 | Mar-23 | - |
| 11 | Premonition | Sony | $44,510,378 | 2,831 | $17,558,689 | 2,831 | Mar-16 | - |
| 12 | Because I Said So | Uni. | $42,674,040 | 2,529 | $13,122,865 | 2,526 | 2-Feb | 4-May |
| 13 | Epic Movie | Fox | $39,700,553 | 2,840 | $18,612,544 | 2,801 | Jan-26 | - |
| 14 | Shooter | Par. | $36,712,076 | 2,806 | $14,523,571 | 2,806 | Mar-23 | - |
| 15 | Freedom Writers | Par. | $36,605,602 | 2,286 | $9,405,582 | 1,360 | 1-May | Mar-15 |
| 16 | Smokin' Aces | Uni. | $35,662,731 | 2,219 | $14,638,755 | 2,218 | Jan-26 | Mar-15 |
| 17 | The Messengers | SGem | $35,374,833 | 2,529 | $14,713,321 | 2,528 | 2-Feb | - |
| 18 | The Number 23 | NL | $35,193,167 | 2,759 | $14,602,867 | 2,759 | Feb-23 | - |
| 19 | Breach | Uni. | $32,958,840 | 1,505 | $10,504,990 | 1,489 | Feb-16 | - |
| 20 | Zodiac | Par. | $32,758,035 | 2,379 | $13,395,610 | 2,362 | 3-Feb | - |
| 21 | Tyler Perry's Daddy's Little Girls | LGF | $31,366,978 | 2,111 | $11,210,754 | 2,111 | Feb-14 | Mar-29 |
| 22 | Hannibal Rising | MGM/W | $27,586,964 | 3,003 | $13,051,650 | 3,003 | 2-Sep | - |
| 23 | Reno 911!: Miami | Fox | $20,306,687 | 2,702 | $10,273,477 | 2,702 | Feb-23 | - |
| 24 | Amazing Grace | IDP | $19,238,386 | 1,162 | $4,054,542 | 791 | Feb-23 | - |
| 25 | The Hills Have Eyes 2 | FoxA | $19,153,873 | 2,465 | $9,686,362 | 2,447 | Mar-23 | - |
| 26 | The Last Mimzy | NL | $18,824,564 | 3,017 | $10,024,819 | 3,017 | Mar-23 | - |
| 27 | Are We Done Yet? | SonR | $18,517,017 | 2,877 | $14,262,724 | 2,877 | 4-Apr | - |
| 28 | Reign Over Me | Sony | $17,344,515 | 1,747 | $7,460,690 | 1,671 | Mar-23 | - |
| 29 | The Hitcher (2007) | Rog. | $16,472,961 | 2,836 | $7,818,239 | 2,831 | Jan-19 | - |
| 30 | Dead Silence | Uni. | $16,298,900 | 1,806 | $7,842,725 | 1,805 | Mar-16 | - |
| 31 | Happily N'Ever After | LGF | $15,589,393 | 2,381 | $6,608,244 | 2,381 | 1-May | Feb-15 |
| 32 | Catch and Release | Sony | $15,539,051 | 1,622 | $7,658,898 | 1,622 | Jan-26 | - |
| 33 | Alpha Dog | Uni. | $15,242,450 | 1,292 | $6,412,775 | 1,289 | 1-Dec | Feb-22 |
| 34 | I Think I Love My Wife | FoxS | $12,297,056 | 1,794 | $5,674,802 | 1,776 | Mar-16 | - |
| 35 | The Reaping | WB | $11,958,518 | 2,603 | $10,025,203 | 2,603 | 4-May | - |
| 36 | Grindhouse | W/Dim. | $11,596,613 | 2,624 | $11,596,613 | 2,624 | 4-Jun | - |
| 37 | The Astronaut Farmer | WB | $10,853,908 | 2,155 | $4,454,319 | 2,155 | Feb-23 | - |
| 38 | Primeval | BV | $10,597,734 | 2,444 | $6,048,315 | 2,444 | 1-Dec | 3-Aug |
| 39 | Black Snake Moan | ParV | $9,288,383 | 1,253 | $4,143,199 | 1,252 | 3-Feb | - |
| 40 | Code Name: The Cleaner | NL | $8,135,024 | 1,736 | $4,244,142 | 1,736 | 1-May | 2-Jan |
| 41 | The Lives of Others | SPC | $7,427,381 | 259 | $213,589 | 9 | 2-Sep | - |
| 42 | The Namesake | FoxS | $6,881,956 | 335 | $248,552 | 6 | 3-Sep | - |
| 43 | Pride | LGF | $6,653,995 | 1,518 | $3,533,300 | 1,518 | Mar-23 | - |
| 44 | Firehouse Dog | Fox | $5,101,907 | 2,860 | $3,838,916 | 2,860 | 4-Apr | - |
| 45 | The Lookout | Mira. | $3,808,036 | 955 | $2,017,795 | 955 | Mar-30 | - |
| 46 | Blood and Chocolate | MGM | $3,526,588 | 1,200 | $2,074,300 | 1,200 | Jan-26 | Mar-29 |
| 47 | The Ultimate Gift | BPic | $3,257,137 | 816 | $1,241,079 | 816 | 3-Sep | - |
| 48 | Ma Fille, Mon Ange | All. | $2,696,995 | 87 | $795,000 | 87 | Feb-16 | - |
| 49 | Guru | AdL. | $2,096,000 | 76 | $760,000 | 71 | 1-Dec | - |
| 50 | Salaam-E-Ishq | Eros | $1,852,050 | 86 | $949,000 | 86 | Jan-25 | - |
| 51 | The Host | Magn. | $1,739,988 | 116 | $314,488 | 71 | 3-Sep | - |
| 52 | The Hoax | Mira. | $1,449,320 | 235 | $1,449,320 | 235 | 4-Jun | - |
| 53 | The Abandoned | ADF | $1,331,137 | 1,000 | $782,000 | 1,000 | Feb-23 | 3-Aug |
| 54 | Eklavya - The Royal Guard | Eros | $1,290,212 | 80 | $690,423 | 80 | Feb-16 | - |
| 55 | Namastey London | Eros | $1,103,808 | 65 | $578,224 | 65 | Mar-23 | - |
| 56 | Thr3e | BPic | $1,008,849 | 458 | $700,000 | 458 | 1-May | - |
| 57 | Avenue Montaigne | Think | $893,602 | 35 | $29,377 | 2 | Feb-16 | - |
| 58 | The Wind That Shakes the Barley | IFC | $750,720 | 39 | $135,554 | 15 | Mar-16 | - |
| 59 | Seraphim Falls | IDP | $418,296 | 52 | $155,560 | 52 | Jan-26 | 3-Aug |
| 60 | The Last Sin Eater | BPic | $388,390 | 429 | $246,483 | 429 | 2-Sep | Feb-22 |
| 61 | The Italian | SPC | $378,312 | 25 | $23,290 | 4 | Jan-19 | - |
| 62 | The 2006 Academy Award Nominated Short Films | Magn. | $320,003 | 38 | $105,709 | 38 | Feb-16 | - |
| 63 | Journey from the Fall | ImAs | $309,372 | 10 | $87,350 | 4 | Mar-23 | - |
| 64 | Constellation | N/A | $306,533 | 238 | $215,801 | 238 | 2-Feb | - |
| 65 | Into Great Silence | Zeit. | $295,559 | 14 | $11,355 | 1 | Feb-28 | - |
| 66 | God Grew Tired of Us | NM | $292,751 | 10 | $21,858 | 2 | 1-Dec | - |
| 67 | Mafioso (re-issue) | Rialto | $254,295 | 7 | $29,965 | 2 | Jan-19 | - |
| 68 | La Vie en Rose | TVA | $245,236 | 42 | $245,236 | 42 | Mar-16 | - |
| 69 | Starter for 10 | PicH | $216,839 | 32 | $37,141 | 20 | Feb-23 | Mar-29 |
| 70 | Believe in Me | IFC | $209,654 | 54 | $81,569 | 54 | 3-Sep | 4-May |
| 71 | An Unreasonable Man | IFC | $150,050 | 11 | $9,813 | 1 | Jan-31 | - |
| 72 | Sharkwater | All. | $144,380 | 20 | $144,380 | 20 | Mar-23 | - |
| 73 | Becket (Re-issue) | Slow | $139,282 | 9 | $7,912 | 1 | Jan-26 | - |
| 74 | Black Book | SPC | $137,034 | 9 | $112,521 | 9 | 4-Apr | - |
| 75 | After the Wedding | IFC | $120,314 | 7 | $47,311 | 5 | Mar-30 | - |
| 76 | Tortilla Heaven | Wildc. | $105,401 | 76 | $73,452 | 76 | Mar-16 | - |
| 77 | First Snow | YFG | $100,519 | 32 | $15,189 | 3 | Mar-23 | - |
| 78 | The Page Turner | Tar. | $95,886 | 15 | $18,844 | 2 | Mar-23 | - |
| 79 | Fido | TVA | $91,879 | 67 | $91,879 | 67 | Mar-16 | - |
| 80 | Comedy of Power | Koch | $80,550 | 2 | $10,061 | 1 | 1-May | Mar-29 |
| 81 | Puccini for Beginners | Strand | $80,042 | 11 | $13,380 | 2 | 2-Feb | - |
| 82 | Killer of Sheep (Re-issue) | Mile. | $76,685 | 2 | $26,154 | 2 | Mar-30 | - |
| 83 | Boy Culture | TLA | $76,659 | 3 | $27,835 | 3 | Mar-23 | - |
| 84 | Nishabd | Eros | $73,819 | 25 | $40,684 | 25 | 3-Feb | - |
| 85 | Gray Matters | YFG | $71,561 | 19 | $25,714 | 15 | Feb-23 | Mar-22 |
| 86 | The Earrings of Madame de... (Re-issue) | Jan. | $70,280 | 1 | $15,409 | 1 | Mar-16 | - |
| 87 | Behind the Mask: The Rise of Leslie Vernon | Anch. | $69,136 | 72 | $38,500 | 72 | Mar-16 | - |
| 88 | Tears of the Black Tiger | Magn. | $68,500 | 5 | $7,954 | 1 | 1-Dec | - |
| 89 | Color Me Kubrick | Magn. | $68,054 | 19 | $37,201 | 19 | Mar-23 | - |
| 90 | Bamako | NYer | $66,559 | 2 | $10,183 | 1 | Feb-14 | - |
| 91 | My Brother | Code | $65,797 | 28 | $28,613 | 28 | Mar-16 | - |
| 92 | Islander | Slow | $56,721 | 11 | $8,871 | 3 | 3-Sep | - |
| 93 | Maxed Out | Magn. | $55,281 | 6 | $20,024 | 6 | 3-Sep | - |
| 94 | Nomad (The Warrior) | Wein. | $51,744 | 60 | $14,250 | 30 | Mar-16 | - |
| 95 | Offside | SPC | $49,735 | 7 | $18,003 | 5 | Mar-23 | - |
| 96 | Beyond the Gates | IFC | $40,848 | 7 | $6,374 | 1 | 3-Sep | 4-May |
| 97 | The Situation | Shad. | $40,131 | 7 | $7,187 | 2 | 2-Feb | - |
| 98 | Black Friday | AdL. | $35,000 | 10 | $25,000 | 10 | 2-Sep | - |
| 99 | The Holy Mountain (re-issue) | Abk. | $34,647 | 3 | $4,143 | 1 | Jan-19 | - |
| 100 | The TV Set | Think | $34,531 | 8 | $34,531 | 8 | 4-Jun | - |
| 101 | The Cats of Mirikitani | LucD. | $29,561 | 1 | $5,160 | 1 | 3-Feb | - |
| 102 | Grbavica: The Land of My Dreams | Strand | $26,252 | 3 | $4,977 | 1 | Feb-16 | - |
| 103 | Cashback | All. | $25,882 | 22 | $25,882 | 22 | Mar-16 | - |
| 104 | Hat Trick | UTV | $24,502 | 24 | $20,700 | 24 | Mar-16 | - |
| 105 | Sacco and Vanzetti | FRun | $23,948 | 3 | $2,778 | 1 | Jan-26 | - |
| 106 | Air Guitar Nation | Shad. | $23,553 | 3 | $7,035 | 1 | Mar-23 | - |
| 107 | Il Ne Faut Jurer de Rien | All. | $23,442 | 6 | $9,836 | 6 | Jan-26 | - |
| 108 | Exterminating Angels | IFC | $23,308 | 2 | $6,485 | 1 | 3-Jul | 4-May |
| 109 | Close to Home | IFC | $20,931 | 6 | $5,630 | 2 | Feb-16 | 4-May |
| 110 | What Love Is | BSky | $18,901 | 42 | $11,583 | 42 | Mar-23 | - |
| 111 | American Cannibal | Life | $16,566 | 1 | $4,778 | 1 | Mar-16 | - |
| 112 | Full of It | NL | $14,273 | 15 | $11,431 | 15 | 3-Feb | 3-Aug |
| 113 | Rock Bottom | Wrin. | $12,890 | 1 | $4,017 | 1 | 3-Feb | - |
| 114 | Live Free or Die | Think | $12,706 | 5 | $8,875 | 5 | Mar-30 | - |
| 115 | Blockade | Icar. | $11,750 | 1 | $5,271 | 1 | Mar-14 | - |
| 116 | East of Havana | BMG | $11,550 | 1 | $4,800 | 1 | 2-Feb | - |
| 117 | Alone with Her | IFC | $10,787 | 2 | $5,555 | 1 | Jan-17 | 3-Jan |
| 118 | Verdict on Auschwitz | FRun | $10,782 | 1 | $2,740 | 1 | 1-Dec | - |
| 119 | Wild Tigers I Have Known | IFC | $9,946 | 1 | $4,515 | 1 | Feb-28 | - |
| 120 | Fighting Words (a.k.a. Street Poet) | Indic. | $9,753 | 3 | $9,753 | 3 | 4-Jun | - |
| 121 | China Blue | Argo. | $9,048 | 3 | $3,767 | 2 | Jan-19 | - |
| 122 | G.I. Jesus | Cnv. | $8,593 | 12 | $6,014 | 12 | Jan-26 | - |
| 123 | Summer in Berlin | DSt. | $8,340 | 1 | $5,536 | 1 | Mar-30 | - |
| 124 | Cobra Verde (Re-issue) | 518 | $7,402 | 1 | $7,402 | 1 | Mar-23 | - |
| 125 | Glastonbury | Think | $7,317 | 3 | $1,179 | 1 | Feb-23 | - |
| 126 | Operation Homecoming | Docu. | $6,795 | 1 | $4,516 | 1 | 2-Sep | - |
| 127 | In the Pit | Kino | $6,683 | 2 | $1,986 | 1 | 2-Feb | - |
| 128 | Fired! | ICir | $5,661 | 4 | $2,158 | 4 | 2-Feb | Feb-15 |
| 129 | Fratricide | Koch | $5,428 | 2 | $4,343 | 2 | Feb-16 | - |
| 130 | Whole New Thing | Pict. | $4,949 | 1 | $4,949 | 1 | 4-Jun | - |
| 131 | The Cop, the Criminal and the Clown | LSeal | $3,935 | 1 | $3,935 | 1 | 4-Jun | - |
| 132 | Funny Money | Think | $2,844 | 4 | $1,839 | 4 | Jan-26 | - |
| 133 | Ten 'til Noon | RadL | $2,520 | 1 | $2,520 | 1 | Mar-30 | - |
| 134 | Race You to the Bottom | Reg. | $2,517 | 1 | $1,549 | 1 | Mar-30 | - |
| 135 | Daratt | Artma | $2,352 | 1 | $2,352 | 1 | 4-Jun | - |
| 136 | The Prisoner or: How I Planned to Kill Tony Blair | RedE | $2,194 | 2 | $2,194 | 2 | Mar-23 | - |
| 137 | Raising Flagg | Libre | $2,004 | 1 | $636 | 1 | 2-Feb | - |
| 138 | The Hawk Is Dying | Strand | $1,904 | 1 | $1,042 | 1 | Mar-30 | - |
| 139 | Los Muertos | Fct. | $1,758 | 1 | $1,758 | 1 | 4-Jun | - |
| 140 | Adam's Apples | Outs | $1,305 | 1 | $1,305 | 1 | Mar-16 | - |
| 141 | Notes on Marie Menken | Icar. | $577 | 1 | $577 | 1 | 2-Sep | - |
| 142 | The Marsh | All. | $336 | 1 | $336 | 1 | Mar-23 | - |